Dr Nick Sireau is co-founder and Chair of Orchard OCD, a charity that develops new and better treatments for obsessive-compulsive disorder (OCD). He is also the CEO and Chair of Trustees at the AKU Society, a patient group that helps people with AKU (short for alkaptonuria), a rare genetic disease affecting both his children. He is co-founder and Chair of Findacure, an organisation that helps many rare disease patient groups. Previously, Nick was the founding CEO of SolarAid, an NGO working in Africa. He is a fellow of the Ashoka Fellowship of Social Entrepreneurs and has a PhD in the social psychology of social movements. He is the editor of ‘Rare Diseases: Challenges and Opportunities for Social Entrepreneurs’ (Greenleaf 2013) and of the ‘Patient Group Handbook: A Practical Guide for Research and Drug Development’ (Findacure 2016).